NIHilist's Immunology

How Immune System works

Showing posts with label haploinsufficiency. Show all posts
Showing posts with label haploinsufficiency. Show all posts
Friday, December 12, 2014

Tolerance in humans is a full-time work: CTLA4 haploinsufficiency

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CTLA4 is a powerful inhibitory molecule required to keep activated T cells in check. For example, mice deficient in CTLA-4 develop fatal mu...
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