NIHilist's Immunology

How Immune System works

Wednesday, January 11, 2023

If T cell clones are so diverse, what prevents anti-tumor immune response?

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Identifying cancer and pathogen-specific epitopes or TCRs may sound intuitive, but it is a futile approach. Diversity of T cell or B cell cl...
Friday, September 18, 2020

A specific bacteria-infecting virus, bacteriophage, found in gut microflora, augments anti-tumor T cell immunity

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Molecular mimicry between microbial and host's antigens could contribute to autoimmunity but also to the protection against tumors throu...
4 comments:
Thursday, August 6, 2020

Is it possible to engineer Foxp3+ Tregs from primary T cells?

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Here is the most recent paper that claims that they can do it. It was published in Science Translational Medicine . This is fairly respectab...
2 comments:
Wednesday, April 15, 2020

Do Tregs inhibit or promote allergic responses? How to avoid data misinterpretation

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Foxp3+ regulatory T cells (Tregs) are the most essential component of the immune system. No other cell population, taken singularly, have s...
4 comments:
Tuesday, January 28, 2020

Microbiota-derived peptide and autoimmune heart inflammation: a tale of missing data

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Papers published in journal Science supposed to undergo thorough high-level vetting process. However, to err is human. Both reviewers and e...
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